La question épineuse, que nous nous posons toutes à fait l’objet d’une causerie éducative samedi 27/08/2016 au siège de l’association.
Comme chaque mois, nos causeries font l’objet de discussions et sont l’occasion de nous retrouver en toute confidentialité.
Le thème de ce mois : le Coming Out, visait spécifiquement à aider nos bénéficiaires à assumer leur orientation sexuelle et à mieux gérer au mieux dans le quotidien, que ce soit dans le couple ou dans le célibat.
Nos discussions ont porté sur de la notion de coming out, sur la découverte des biens faits du coming out, et la gestion au quotidien sa sortie du placard ! face à son entourage.
Sur l’acte en lui, il des questions pratiques posées : avec qui parler de sa sexualité ?, quand le faire et surtout comment le faire ?!
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Tous, enroulées dans une discussion des plus passionnantes – le mot étant bien approprié- pendant 3 heures.
Comme à l’accoutumé , cette causerie était basée sur une approche participative, essentiellement construite d’échanges interactifs et de brainstorming.
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Amongst the artificial steroids of therapeutic value are
numerous anti-inflammatory agents, anabolic (growth-stimulating) agents, and oral contraceptives.
These doses are a lot higher than people who health care suppliers use for medical
causes. These medicine may lower the injury that happens to muscle tissue during a hard workout.
The condition known as sleep apnea (which causes people to
cease breathing for brief intervals during sleep) is worsened by
taking anabolic steroids, as are tics, or muscle twitches, in those
that already suffer from them. Although anabolic steroids are typically referred to simply as
steroids, they are in reality only one sort of steroid. They are to not
be confused with corticosteroids, such as prednisone and cortisone, that are commonly used to treat sicknesses similar to
arthritis, colitis, and asthma. Avenue or slang phrases for anabolic steroids embody « roids » and
« juice. » Testing for anabolic steroids has come a long way because the Seventies, when fundamental radioimmunoassay methods had been used.
Today, anabolic steroids and their metabolites can usually be detected in urine,
using mass spectrometry. Amongst AAS customers there may be
the idea that AAS might trigger gynecomastia through different pathways,
corresponding to increased progestin motion on the mammary glands or elevated prolactin ranges.
The versatile steroid Deca Durabolin is often used in a bulking cycle.
This is because it tends to advertise muscle progress and
increase energy and endurance for a competitive advantage.
Deca Durabolin, nevertheless, causes critical well being issues and
the side effects of abusing anabolic steroids, very similar to Dianabol does.
Decaduro, which is its natural equivalent, is a far wiser various.
Anabolic steroids may be given orally, intramuscularly, or subcutaneously by way of creams or gels, relying
on the kind. Anabolic steroids are taken orally, subcutaneously, or intramuscularly, as pellet injections beneath the pores
and skin, or topically as gels or patches when they are used for medicinal functions.
However there isn’t any proof that creatine helps
you do better at sports activities that make you breathe at a higher
rate and raise your coronary heart price, referred to as cardio sports activities.
It additionally raises the levels of the protein in red blood cells that
carries oxygen to the body’s organs, known as hemoglobin. Study
more about the results that performance-enhancing medicine can have on health.
Nonetheless, they may compound the cardiovascular threat imposed
by the opposite atherogenic results of AAS, similar to dyslipidemia, performing as potential CVD risk modifiers.
In hypertensive individuals, LV mass corrected for physique surface area provides prognostic
worth for ischemic coronary heart illness and coronary heart
failure in addition to established (SCORE) risk elements (218).
The identical holds true for world longitudinal
strain in nonhypertensive people (218).
Thus, customers can expect a remarkable enhance in fat-free mass but
additionally a significant quantity of (temporary) water retention. Anadrol will cause hefty
weight acquire, roughly 30 lbs from a cycle, as
a result of it being a moist steroid in addition to anabolic.
In this guide, we will listing the different sorts of bulking and cutting steroids utilized
by our sufferers, comprehensively detailing their advantages and unwanted side effects.
We will listing in brackets whether or not they’re oral or injectable steroids.
The long-term consequences of steroid use can vary by gender,
with potential irreversible results in girls and younger customers.
General, whereas anabolic steroids could provide short-term benefits in muscle growth and athletic performance, they carry vital dangers that warrant
warning and consciousness. The most interesting anabolic steroid for muscle development is Dianabol, which increases testosterone synthesis to extend strength
and bulk.
Testosterone, and its estrogenic metabolite estradiol, exert adverse suggestions on the hypothalamus and pituitary to suppress their own synthesis (173, 174).
Estradiol in particular is extraordinarily potent at suppressing gonadotropin secretion as,
on a molar basis, it’s estimated to be 200-fold stronger than testosterone in doing so (175).
Consequently, exogenously administered AAS may even exert negative suggestions, thereby suppressing testicular testosterone production and spermatogenesis.
Nevertheless, since not all AAS users completed comply with up, attrition bias may
additionally (partly) clarify the difference.
Regardless, erectile dysfunction might develop after an AAS cycle on account of the transient
hypogonadal state. In this case a loss of libido as
a outcome of testosterone deficiency usually underlies the erectile dysfunction. The mechanism for this
is unclear, however, given that estradiol,
independently of testosterone, also performs a role in regulating erectile perform (194), it would
involve an imbalance between androgenic and estrogenic action. Erectile dysfunction may also
be a consequence of psychological factors, as libido might rise
sharply in an AAS user during the cycle and infrequently hinder a healthy
and mutual sexual relationship. Public discourse usually consists of
misconceptions about anabolic steroids. Some imagine
these medication cause exaggerated bodily modifications unrelated to muscle development.
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What might change is your training and diet to tweak
the results according to personal objectives. You can’t
go incorrect with Dianabol or Anadrol for a blasting part or another compounds talked about above
for cutting cycles. You could use just about any quick injectable ester or
oral steroid as a secondary compound in a 6 to 8-week cycle.
The typical decisions are Anadrol, Winstrol,
Trenbolone Acetate, Masteron Prop, Dianabol,
and Anavar. At the lower finish, below 500mg, you’re taking a glance at testosterone substitute and
a few noticeable enhance to vitality, strength, restoration, and positive aspects.
Nonetheless, taking no much less than 500mg weekly is commonplace, often increasing to 1000mg
for important positive aspects. Hardly Ever will it’s
essential to increase the Take A Look At dosage to anywhere close to 2000mg.
This testosterone ester is a long-acting steroid with a half-life of 8-12 days.
This means it’s slow-acting in comparison with another
testosterone esters, and it could take four or more weeks till you
begin seeing noticeable enhancements in strength, typically so long as
six weeks. Even a low dose of testosterone can provide a stable enhance
to performance and positive aspects, and if you’re starting, you may need to check the waters with the lowest, most
effective dosage. These so-called mild cycles of around 250mg per week
still provide benefits while reducing the impression of unwanted effects.
A typical cycle of this sort would include Testosterone Cypionate at
500mg weekly and Deca at 400mg weekly for 12
weeks.
In particular, an affiliation between testosterone therapy and prostate most cancers was rapidly drawn primarily based
on animal experiments and restricted case studies (81). Notably,
the ventral prostate of the rat turned the model organ for androgenic activity in the famend Hershberger androgen bioassay, which was developed in 1953 (82).
Whereas a severely flawed strategy, the bioassay stays in use today, to some
extent, in the quest for selective androgen receptor modulators (SARMs)
(83, 84). Men over 40 years of age with baseline prostate-specific antigen (PSA) of greater than zero.6 ng/mL ought to have their PSA ranges measured and a prostate examination at 3 to six months.
Treatment ought to be withheld in men with a palpable prostate nodule or prostate-specific antigen of more than four ng/mL
and in patients at excessive danger of prostate malignancy with
prostate-specific antigen of more than 3 ng/mL. A well-structured cycle
can convey vital muscle growth, improved energy, and a extra outlined
physique, particularly when mixed with correct coaching and vitamin.
Understanding your starting body weight helps you plan acceptable dosing and
observe progress during your cycle.
It’s like a broken record trying to explain the fundamentals to some
guys who don’t know what they’re moving into.
Thanks to some recent updates, the essential characteristic of plotting steroid compounds is now accessible
with out an account. The formula behind our Steroid Conversion Calculator
is vital to convey precise conversion results. It optimizes the calculation course of, saving time whereas ensuring accuracy.
Understand the significance and mechanics of this method as we delve
into its specifics.
One really helpful dosage is 40mg daily in the first week,
20mg day by day for the subsequent two weeks, and 10mg day by day for the fourth and ultimate week.
In a 3-week protocol, one of many recommended dosages is to take
100mg on the primary day, followed by 60mg for 10 days, then drop to 40mg for the ultimate 10 days.
Clomid is likely considered one of the most generally used
SERMs among steroid customers to revive natural testosterone-producing function. It’s cheap and
available, so it’s typically the first SERM we turn to.
For these in search of extra complex strategies, the calculator provides
superior options. You can set preferences for frontloading,
tapering strategies, and even graph displays. This flexibility allows users to tailor
their cycles additional and visualise their plans successfully,
making the expertise extra user-friendly and informative.
To run a PCT cycle using Raloxifene, take a look
at my in-depth Raloxifene PCT information. If the person’s aim is bulking to add huge muscle mass growth, they can select Dianabol,
Anadrol, Testosterone, Deca Durabolin, and Trenbolone.
If the person’s goal is for a slicing cycle to eliminate excess body
fat, they will select Anavar, Winstrol, Clenbuterol, Primobolan, Equipoise, and Cytomel T3.
PCT will prevent you from struggling low testosterone symptoms
and supply that bridge you want to function nicely and maintain your gains whereas your testosterone perform steadily restores itself.
In Style oral steroids that can be stacked with Testosterone Cypionate embrace Anadrol,
Anavar, Dianabol, and Winstrol. In cases where men are strongly predisposed to hair loss,
shampoo like Nizoral, which topically blocks androgens immediately
on the scalp, can add another layer of mitigation in direction of
this facet effect. Some individuals will successfully use
Nizoral 2% shampoo to treat steroid-induced acne.
In the HAARLEM study, a transient small improve in serum creatinine concentrations of unknown clinical relevance was observed throughout AAS use (from 93.1 μmol/L (1.05 mg/dL) to 97.eight μmol/L (1.eleven mg/dL)).
Creatinine concentrations returned to baseline after cessation of use.
Albuminuria, as measured by dipstick analysis, emerged or increased in 16%
of the topics (155). In these receiving 1-androsterone,
serum creatinine levels elevated considerably from 97.three μmol/L (1.1
mg/dL) to one hundred fifteen.zero μmol/L (1.three mg/dL).
The general medical effects, nevertheless, are crystal clear
– initially the muscle-building effect pursued by AAS customers.
More recent well-designed trials continued to provide
further support for the potent muscle-building results of AAS that had already been recognized
by athletes for decades (15, 22, 35–38).
Additionally, you won’t want the long-term HGH use on a 12-week cycle, but it
helps improve gains during the cycle (as are others like IGF).
One of the largest challenges in a regular bulking cycle is controlling water weight, sustaining features
via efficient anti-estrogens, and implementing PCT. You’re
almost at all times higher off adding secondary compounds as a substitute of taking an extreme testosterone dose.
How much you achieve and preserve after each cycle will come
down to personal factors, but even a 5-10lbs maintainable achieve from every cycle will accumulate through the years.
The time scale of 10 to 12 weeks makes it attainable to combine nearly
any compounds with different size esters, primarily allowing
you to tailor either a bulking or chopping cycle according to your
personal goals. When you start precisely depends on the esters
used and their clearing time. Still, the standard Testosterone
enanthate or similar size Take A Look At ester often sees a 2-week clearing time following your
last steroid shot.
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The comparison of ipamorelin, tesamorelin and sermorelin is
often asked by people who are interested in peptide therapy for body composition, anti-aging
or clinical conditions such as HIV-associated
lipodystrophy. Each of these peptides has a distinct
mechanism of action, therapeutic niche and side-profile that can be understood by looking at their pharmacology,
approved uses and practical experience.
Tesamorelin vs Sermone: Which Peptide Fuels
Fat Loss and Recovery?
Both tesamorelin and sermone are synthetic analogues of growth hormone releasing hormone (GHRH).
They bind to the GHRH receptor on pituitary cells
but they differ in their potency, half-life and downstream effects.
Because of its higher affinity for the receptor and longer duration of
action, tesamorelin is more effective at stimulating endogenous growth hormone release
than sermone. This translates into a greater reduction of visceral adipose
tissue when used chronically. In patients with HIV-associated lipodystrophy, daily subcutaneous
injections of 2 mg tesamorelin for up to 48 weeks have produced a mean decrease in abdominal fat volume of about 20 percent and an improvement in insulin sensitivity that is not seen with sermone at the same dose.
Sermone, on the other hand, has a shorter half-life and elicits a smaller peak in growth
hormone secretion. It is therefore less
effective as a stand-alone agent for fat loss but it can be used safely to stimulate muscle anabolism or support recovery after surgery when combined with anabolic steroids
or protein supplementation.
Overview of Tesamorelin and Sermone
Tesamorelin (brand name Egrifta) was approved by the Food and Drug Administration in 2010 specifically for reduction of excess
abdominal fat in adults with HIV infection who have a high visceral adipose
tissue volume. It is administered as a 2 mg
subcutaneous injection once daily. The drug stimulates growth hormone release,
which in turn increases lipolysis in visceral adipocytes and enhances
insulin sensitivity.
Sermone (brand name Serostim) has been on the market for many years as a therapy for growth hormone deficiency in adults and children. It is also used off-label for weight loss, muscle
wasting or as an adjunct to other anabolic therapies.
Sermone is given at doses ranging from 1 mg to 3 mg per day subcutaneously,
usually divided into two injections.
How Tesamorelin Works
Tesamorelin mimics the natural peptide GHRH by binding to its receptor on pituitary somatotrophs.
This activation triggers a cascade of intracellular events that culminate in the synthesis and release
of growth hormone into the bloodstream. Once released, growth hormone travels to peripheral tissues where it binds to the growth hormone receptor and activates signaling pathways that promote lipolysis,
protein synthesis and cell proliferation.
In visceral fat cells, growth hormone increases the activity of hormone-sensitive lipase, which breaks down triglycerides into free fatty acids that are
then released into circulation. The rise in circulating free fatty acids provides a fuel source for oxidative metabolism and reduces the storage of excess calories as adipose tissue.
In addition, growth hormone improves insulin sensitivity by reducing hepatic glucose production and
increasing peripheral uptake of glucose.
Because tesamorelin’s effect is mediated through the body’s own endocrine system,
it avoids many of the adverse effects associated with direct administration of
exogenous growth hormone, such as fluid retention or arthralgia.
However, because it still increases endogenous growth hormone levels, it can cause transient increases in blood
sugar and may need to be monitored in patients with
diabetes.
In clinical practice, tesamorelin is typically started at 1 mg per day and titrated up to 2 mg once daily after
an initial assessment of tolerance. The drug should be used for a minimum of 12 weeks dianabol before and after evaluating changes in visceral
fat by imaging or anthropometric measurements.
If no significant improvement is seen after 48 weeks,
discontinuation may be considered.
Conclusion
While all three peptides stimulate growth hormone release,
tesamorelin stands out as the most potent agent for targeted reduction of abdominal adiposity and
for improving metabolic parameters in HIV-associated lipodystrophy.
Sermone remains a useful tool for treating growth
hormone deficiency and supporting muscle recovery but is less
effective for fat loss when used alone. Ipamorelin, not discussed in detail here, offers a different profile with
a more selective action on the ghrelin receptor that can promote appetite and lean mass while sparing visceral fat.
Each peptide should be chosen based on the patient’s specific
clinical goal, comorbidities and tolerance to hormone therapy.
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Testosterone Replacement Therapy: Injections, Patches, And Gels
Is Testosterone Replacement Therapy Right for You?
Deciding whether testosterone replacement therapy
(TRT) is right for you involves considering your health history, current symptoms,
and professional advice. TRT is not a one-size-fits-all treatment; it should be tailored to individual needs based on lab results and medical evaluations.
What Is Testosterone Replacement Therapy?
Testosterone replacement therapy involves the administration of testosterone
or its derivatives to individuals who are deficient in this
hormone. Low testosterone levels can lead to a variety of physical and emotional symptoms, and TRT aims to restore these levels to a healthy range.
Low Testosterone Causes
Low testosterone is often caused by aging, genetic factors, certain medical conditions, or lifestyle choices.
Factors like obesity, insufficient sleep, and chronic stress can also contribute
to low testosterone levels.
Subtle Symptoms of Low Testosterone
Symptoms of low testosterone may be subtle but can significantly impact quality of life.
These include fatigue, mood swings, decreased libido, difficulty concentrating, and physical changes such as muscle
loss or weight gain.
How Are You Tested for Low Testosterone?
Testing for low testosterone typically involves blood tests to measure hormone levels.
Doctors may also assess symptoms and medical history to determine if treatment
is appropriate.
Forms of Testosterone Supplements
TRT can be delivered through various forms, including injections, patches,
gels, and oral supplements. The choice of form depends on individual preferences
and medical recommendations.
Benefits of Testosterone Therapy
Testosterone therapy can provide numerous benefits, including improved energy levels, better mental clarity, enhanced libido, and muscle strength.
It may also help in managing conditions like
obesity and diabetes.
Is Testosterone Replacement Therapy Safe?
The safety of TRT depends on the dosage, form, and duration of
treatment. While it can be effective, potential risks include side effects
such as acne, hair loss, and mood changes. Long-term use
requires careful monitoring.
Testosterone Replacement vs. Performance-Enhancing Steroids
TRT is different from performance-enhancing steroids (PEDs).
TRT aims to treat hormone deficiency, while PEDs are used to
enhance athletic performance or improve appearance beyond natural capabilities.
How to Get Testosterone Replacement Therapy
To get TRT, you must consult a healthcare professional who can assess your hormone levels and recommend an appropriate treatment plan. Self-prescription is not recommended due to the potential
risks involved.
Takeaways
TRT can be a valuable tool for managing low testosterone levels, but it should only be used under medical supervision. Understanding
the benefits, risks, and alternatives is crucial before starting any treatment.
Testosterone Replacement Therapy FAQs
Q: Can women use TRT?
A: While TRT is primarily prescribed for men, there are rare instances where women may benefit from it due to conditions like hypogonadism.
Always consult a doctor for advice.
More On Men’s Health
Explore other topics related to men’s health, including prostate
health, erectile dysfunction, and aging gracefully.
Essential Screening Tests Every Man Needs
Men should prioritize regular health screenings, including blood tests
for testosterone levels, cholesterol, and glucose to monitor overall health and catch potential issues early.
Ways for Men to Look Great as They Age
Men can maintain their appearance and confidence
through healthy aging strategies, such as proper nutrition, exercise,
and skincare.
Health Maintenance Tips for Men
Maintaining health involves a combination of regular check-ups,
a balanced diet, and lifestyle habits that promote well-being.
Routine exercise, stress management, and adequate sleep are essential for men’s health.
FEATURED
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The Best Steroid Cycles: Everything You Need To Know
steroids have been a widely discussed topic in the world of fitness and bodybuilding.
they are synthetic substances that mimic the effects of hormones in our bodies, particularly testosterone.
steroid cycles refer to the period during which individuals
administer these substances in a structured manner to achieve specific physiological or
aesthetic goals.
What Are Steroid Cycles?
steroid cycles involve the use of anabolic steroids, which are chemically similar to testosterone, alongside
other performance-enhancing substances. these cycles
are typically designed to maximize muscle growth, fat loss, and overall physical performance.
they can vary in duration from a few weeks to several months, depending on the goals and
experience of the user.
Popular Steroid Cycles
some of the most common steroid cycles include:
Beginner Cycle: Testosterone (like TestoMax or Testonea) paired with a mild anabolic like Anavar (Oxandrolone) for 8-12 weeks.
Intermediate Cycle: A mix of stronger anabolics like Dianabol (methandrostenolone), Testosterone, and perhaps Halotestin or Anadrol (oxymetholone) for 12-16 weeks.
Advanced Cycle: High-dose testosterone variants (like Testosterone enanthate or cypionate), coupled with stronger anabolics like Trenbolone, and possibly growth hormones for 18-24 weeks.
How to Choose the Right Steroid Cycle
the right steroid cycle depends on your individual
goals, experience, and tolerance. it’s crucial to consider factors like:
Your current level of physical conditioning.
Your target muscle mass or fat loss goals.
The availability of high-quality steroids and other necessary supplements.
Legal and health considerations.
always consult with a medical professional before starting any steroid cycle.
misuse of anabolic steroids can lead to severe health consequences,
including liver damage, cardiovascular issues, and hormonal imbalances.
this information is provided for educational purposes only, and it’s crucial to understand
the legal and ethical implications of using performance-enhancing
substances.
# The Best Steroid Cycles: Everything You Need To Know
## Gender
The gender of an individual significantly influences their steroid cycle experience.
Men and women respond differently due to hormone variations, particularly in estrogen levels for women. This can affect
how they metabolize steroids and the types used.
## Experience Level
Steroid effectiveness varies with experience. Novices typically opt
for milder, shorter cycles to minimize side effects, while intermediates and advanced users may use more potent compounds over longer periods.
## Fitness Goals
Fitness goals determine cycle choices:
- **Bulking** focuses on muscle gain using anabolic steroids like Testosterone or Dianabol.
- **Cutting** aims to reduce fat without muscle loss,
often using less intense compounds or shorter cycles.
## The Differences Between Male & Female Steroid Cycles
Men and women experience different reactions due to hormone differences.
Women may face more estrogen-related side effects, necessitating specific cycle considerations to avoid
virilization.
## Steroid Cycles For Men
Men benefit from various cycles based on goals:
- **Bulking:** Testosterone, Dianabol for mass gain.
- **Cutting:** Clenbuterol or T3 for fat loss without muscle reduction.
## Steroid Cycles For Women
Women focus on body recomposition using less androgenic steroids to minimize side effects like virilization.
## Experience-Based Cycles
Beginners start with shorter, milder cycles, transitioning to longer, more
potent ones as they gain experience. This progression balances effectiveness with reduced risk.
## Lifestyle Considerations
A supportive lifestyle—proper diet, exercise,
sleep, and stress management—is essential for effective steroid cycles.
These factors enhance results and safety.
## TRT & Bridging Cycles
Testosterone Replacement Therapy (TRT) helps maintain gains post-cycle.
Bridging cycles involve low-dose testosterone to prevent muscle loss between steroid use.
## Conclusion
Understanding gender, experience, goals, and lifestyle is crucial for optimal steroid cycling.
Proper planning and maintenance ensure both safety and
effectiveness, summarizing the complexities involved in steroid
use.
# References
- Differential Effects of Protein Supplements(#)
- Evolving Injury Patterns(#)
- Mastering Atlas Stones(#)
# Recent Posts
- Injury Impact on Weightlifters(#)
- Strongman Techniques(#)
# Popular Posts
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